Associate Process Scientist

Ocean Ridge Biosciences (ORB) is currently seeking a highly-motivated and entrepreneurial individual to fill the position of Associate Process Scientist.

Description: The Associate Process Scientist will perform contract experiments for ORB clients including DNA microarray hybridizations, mRNA and small RNA sequencing, real time PCR, and multiplex immunoassays. Duties will include isolation of RNA and DNA from multiple sources, performing assays in the laboratory, data processing, statistical analysis, pathway analysis, and preparation of detailed reports for customers. Additional responsibilities will include maintaining equipment and facilities, ordering supplies, receiving samples, shipping samples, and extensive record keeping. As a key member of the ORB team you will also contribute to sales and marketing by maintaining regular contact with customers throughout their projects, and by providing pre- and post-sales technical support.

Requirements: The Associate Process Scientist will possess an A.A. or B.S. degree with coursework in chemistry, biology and mathematics and three or more years of experience in laboratory molecular biology. The ideal candidate should have substantial experience performing RNA extraction and purification, amplification and labeling of RNA and DNA, sequencing, and immunoassays. We also require proficiency in Microsoft Office products including the analysis and plotting of data in Excel. Basic laboratory math skills and some knowledge of statistics will be essential. Experience with microarrays, NextGen sequencing, and microsphere-based assays would be advantageous. The successful candidate will also demonstrate superior presentation, writing, and oral communication skills. A strong work ethic, entrepreneurial spirit, and consistent positive attitude are required. Neatness, attention to detail, and a willingness to keep careful records are also critical.

Compensation: Base salary commensurate with experience, performance-based bonuses, paid vacation, reimbursement for privately-obtained health insurance.

Project Scientist - Molecular Biology

Ocean Ridge Biosciences (ORB) is seeking a Project Scientist with experience in molecular biology to join a team of highly motivated molecular biologist focused on providing cutting-edge services in the fields of RNA Profiling and Biomarker Discovery.

Description: The Project Scientist will undertake a variety of challenging contract research projects directed and funded by ORB’s clients who include major research laboratories as well as the drug and biomarker discovery departments of pharmaceutical and biotechnology companies. The projects will include investigation of RNA and protein expression, DNA methylation, DNA polymorphisms, and enzymatic activity, in a variety of samples types including whole blood, plasma, and tissue samples from human, mouse, rat and other species.

The Project Scientist’s role will begin with initial consultation with the client concerning their project goals and will include extraction of proteins, DNA, and RNA, performing assays, data analysis, preparation of reports, and post-project consulting. Assays performed by the project scientist will include multiplex bead-based protein and RNA expression assays, next generation sequencing, real-time PCR, Nanostring, and related protocols. Data analysis and preparation of reports will be conducted with the direction and assistance of ORB’s computational biology team. Follow-up conference calls and meetings with clients will be critical to insuring that ORB’s customers are able to fully utilize the information provided in its reports and allows for continuous improvement of processes at ORB.

Requirements:  The candidate will possess a masters or doctoral degree in genetics, biochemistry, molecular biology, genomics, or related discipline. At least four years of recent experience working in a disease research, biochemistry, molecular biology, genomics or related lab type is required. ORB maintains Good Laboratory Practice (GLP) standards; thus the ability and willingness to maintain detailed records of experiments is critical for the job. The position requires excellent technical writing skills which must be demonstrated by authoring of research manuscripts, magazine articles, dissertations, white papers, or technical manuals that are available to the hiring manager for review. Further, the ability to assemble, manipulate, analyze and present biological research data is a must. The individual must be able to simultaneously manage multiple client projects; having the ability and willingness to work directly at the bench as well as assist the bioinformatics team with analyses. Candidates with at least two years of private sector work experience will be favored, even if private sector experience does not relate directly to ORB’s business.

Benefits: The Project Scientist will have a unique opportunity to contribute to the development of new genomics-based medications and companion diagnostics in the field of oncology, autoimmune disorders, ocular disease, diabetes and obesity, neurological disorders, orphan genetic disorders, and infectious disease. The base pay range is $60K - $90K depending on academic credentials and experience. ORB provides medical, dental and vision insurance, as well as paid vacation, sick, and holiday pay. The Project Scientist will be eligible for performance based bonuses and an equity sharing plan.

Staff Scientist – Bioinformatics

ORB is currently seeking a highly-motivated and entrepreneurial scientist to fill the position of Staff Scientist – Bioinformatics.

Description: The selected candidate will design and implement a software infrastructure at ORB for semi-automated processing and statistical analysis of genomics data derived from microarray and deep sequencing projects. The individual will take advantage of existing commercial software packages, open source applications, and script development tools to implement flexible data analysis pipelines that can be tailored to meet the specific needs of ORB clients. Custom scripts and applications will also be developed in Visual Basic, R, Perl, Python, Java, and other languages. The Staff Scientist – Bioinformatics will also supervise a project to enhance the biological sample workflow system at ORB. In addition to software development, the selected individual will also manage genome analysis projects for individual clients.

Requirements: The ideal candidate will possess a M.S. or Ph.D. in the physical or life sciences, and will have three or more years of recent experience in bioinformatics. The position requires proficiency in statistics and coding experience in two or more high-level scripting/programming languages including Visual Basic, R, Perl, Python, and Java. The candidate should have experience with multiple commercial and open source tools/platforms for processing of microarray and deep sequencing data (e.g. Bioconductor, Bowtie, Cufflinks, Trinity). Working knowledge of the Linux operating system, server maintenance, and the Unix Shell command interface is also required. Familiarity with advanced statistical algorithms for biomarker selection and linear modeling of expression data would be a plus, as would experience with analysis of microarray- and sequencing-based CGH, genome-wide methylation, and Chip data sets. Prior wet-lab experience in genomics would also be helpful but not essential.
The successful candidate will also demonstrate superior presentation, writing, and oral communication skills. A strong work ethic, entrepreneurial spirit, and consistent positive attitude are required. Neatness, attention to detail, and a willingness to keep careful records are also critical. Three or more years of work experience in a for-profit business is preferred but not required.

Compensation: Base salary commensurate with experience, plus bonuses and stock options.

Technical Sales Associate

ORB is currently seeking a Technical Sales Associate, to join a team focused on driving sales of ORB's line of high performance genome analysis and biomarker discovery services into the Life Sciences Marketplace. This is an entry- to mid-level position for an individual with a background in the Biological Sciences and Sales that is motivated to achieve maximum earnings potential while gaining first hand knowledge and training in the fields of genomics, drug discovery, and drug development.

Responsibilities: The Technical Sales Associate will be responsible for understanding ORB's services in the Basic Research, Drug Discovery & Drug Development market sectors and for contributing to the maintenance of a focused database of scientists conducting innovative research throughout the United States who could benefit from ORB services. This individual will be responsible for the development of a pipeline of appointments with Biotech Executives and Scientists via efficient e-mail and telephone marketing campaigns as well as in-person “cold calls”. The Technical Sales Associate will also manage to effectively communicate the benefits of ORB services to potential customers at Academic Institutes and Biotechnology Companies in on-site meetings, and maintain relationships with potential and current customers in order to close sales in an expeditious manner. Additional duty will involve representing ORB at Scientific Meetings, Symposia, and Industry Trade Shows.

Requirements: The position requires a BS in Molecular Biology, Chemistry, or other Life Sciences discipline, or equivalent experience. Candidate must have experience in sales with demonstrated ability to attract new customers and close sales. We also require proficiency in Microsoft Office products and databases. The position requires excellent oral and written communication skills, solid self-management, organizational, and prioritization skills. Familiarity with second-generation sequencing applications such as the analysis of mRNA, small RNA, exomes, methylation, and oncogene would be a plus. Working knowledge of the Drug Discovery and Drug Development processes as well as the market participants is advantageous. Must be able to travel up to 33% of the time.

Application Procedure

Please submit a cover letter describing your reasons for applying to ORB along with a resume that highlights your experiences and skills that are relevant to the position to: orbjobs@oceanridgebio.com