Genomic & Biopharma News

AstraZeneca drug heads to phase 2 in pancreatic cancer after small trial extends survival
University of Michigan researchers are reporting promising results from an early trial of AstraZeneca’s AZD1775, a drug that blocks an enzyme cancer cells need to repair their own DNA.
Fierce Biotech, 2019-08-15 11:48:10

FDA cites solvent recovery firm as a player in the valsartan mess
The FDA upended the entire landscape for makers of sartan-based blood pressure medicines after finding some contained potential carcinogens. Now, the FDA is trying a new tack. 
Fierce Pharma, 2019-08-15 11:43:07

New test reveals truth behind gluten-free labels
Many people have wondered whether the gluten-free labeling on their groceries was true. Now, scientists in Australia have come up with a way to identify the presence of specific glutens in rye that indicate the presence of this grain in foods labeled “gluten-free”. Gluten is already known to be present in wheat, barley and oats.
News Medical Life Sciences, 2019-08-15 11:32:33

Circulating tumor DNA evaluated as an alternative to tissue NGS for non-small cell lung cancer
Tissue biopsies, which are currently the gold standard molecular diagnostic technique for oncologists, are not only painful to cancer patients, but expose an already immune-comprised population to increased rates of nosocomial infections. Furthermore, it is not uncommon for the typical clinical pathology workflow to yield samples which are not suitable for routine analysis strategies, e.g.
ORB Company Blog, 2016-10-21 17:26:00

‘Probe’ could help make prostate cancer surgery more accurate
The new project could ‘help surgeons to visualise tumours during keyhole surgery’.
PharmaTimes, 2019-08-15 11:05:14

Celebration to Commemorate Ocean Ridge Biosciences' Re-Opening at New Facility
Ocean Ridge Biosciences (ORB), a leader in RNA profiling and biomarker discovery services, will celebrate a grand re-opening at its new location, 394 SW 12th Avenue, Deerfield Beach, Florida. The event will take place on Friday, November 18th, 2016 from 5:00PM to 8:00PM. Please read the PDF for more details
ORB Company News, 2016-11-14 17:41:06

Urgent medical delivery service set up in Brexit preparations
The £25 million contract to set up an express freight service aims to be completed in the next one to four days.
PharmaTimes, 2019-08-15 10:59:33

Evinacumab hits targets in late-stage cholesterol trial
On average patients entered the trial with LDL cholesterol levels of 255 mg/dL, despite treatment with other lipid-lowering therapies.
PharmaTimes, 2019-08-15 10:50:12

Taltz trumps Tremfya in plaque psoriasis study
The drug met the primary and all major secondary endpoints up to week 12 in the Phase IV IXORA-R study.
PharmaTimes, 2019-08-15 10:41:54

Tighter blood pressure control could improve brain health finds study
Tighter blood pressure control is standard practice in hypertension therapy. Researchers have found that in addition to the benefits this provides to the heart and the vascular system, it also helps lower the risk of cognitive decline and dementia associated with age
News Medical Life Sciences, 2019-08-15 09:03:51

Removal of a critical enzyme may help cases of sepsis finds research
Scientists at the University of California San Diego School of Medicine have shown that removal of an enzyme called the PH domain Leucine-rich repeat Protein Phosphatase 1 (PHLPP1) could help laboratory mice with sepsis in a model they had created for their experiment. The study titled, “PHLPP1 counter-regulates STAT1-mediated inflammatory signalling,” was published this week in the journal eLife.
News Medical Life Sciences, 2019-08-15 08:50:38