Genomic & Biopharma News

Xenon acne drug misses efficacy endpoints in phase 2
Xenon acne drug misses efficacy endpoints in phase 2 nptaylor Fri, 03/24/2017 - 07:47
Fierce Biotech, 2017-03-24 11:47:03

CountClust – visualizing the structure of RNA-seq expression data using grade of membership models
Grade of membership models, also known as “admixture models”, “topic models” or “Latent Dirichlet Allocation”, are a generalization of cluster models that allow each sample to have membership in multiple clusters. These models are widely used in population genetics to model admixed individuals who have ancestry from multiple “populations”, and in natural language processing to ...
Transcriptome Research & Industry News, 2017-03-24 11:45:18

First Humira biosimilar approved in Europe
Amgen has won European approval for its first biosimilar, a version of AbbVie’s blockbuster Humira (adalimumab).
PharmaTimes, 2017-03-24 10:51:49

MSK scientists discover epigenetic mechanism promoting breast cancer
Researchers from Memorial Sloan Kettering Cancer Center (MSK) have identified, for the first time, an epigenetic mechanism promoting breast cancer.
News Medical Life Sciences, 2017-03-24 10:34:28

Researchers describe set of observable characteristics linked to congenital Zika syndrome
Even as the Zika virus becomes more prevalent — the Centers for Disease Control reports that the number of U.S. infants born with microcephaly and other birth defects is 20 times over the normal rate — researchers are still trying to fully pin down the identifying consequences of the viral infection.
News Medical Life Sciences, 2017-03-24 10:03:48

Potential prostate cancer target identfied by RNA-Seq
Prostate cancer patients have been offered hope after scientists at Newcastle University have identified a new group of molecules that could be targeted to slow tumour growth. Experts used RNA sequencing to identify hundreds of genes were affected by the male hormone testosterone. It is believed this could lead to new diagnostic tests and treatments. ...
Transcriptome Research & Industry News, 2017-03-24 10:00:59

Translating the ribosome’s grim role
A large number of long noncoding RNAs (lncRNA) have been found associating with the ribosome, the protein-making machinery in the cytoplasm. What the so-called ‘noncoding’ RNAs are doing on the ribosome, whose main job is to translate RNA into protein, has puzzled the A*STAR researchers who discovered them. The answer could be macabre, suggest cell ...
lncRNA Research and Industry News, 2017-03-24 10:00:53

Non-invasive prostate cancer diagnosing, monitoring
Technology being developed at Washington State University provides a non-invasive approach for diagnosing prostate cancer and tracking the disease’s progression. The innovative filter-like device isolates prostate cancer indicators from other cellular information in blood and urine. It could enable doctors to determine how cancer patients are responding to different treatments without needing to perform invasive ...
Exosome RNA Research & Industry News, 2017-03-24 10:00:07

Random DNA copying ‘mistakes’ account for most cancer mutations, study finds
Johns Hopkins Kimmel Cancer Center scientists report data from a new study providing evidence that random, unpredictable DNA copying "mistakes" account for nearly two-thirds of the mutations that cause cancer.
News Medical Life Sciences, 2017-03-24 09:57:29