Genomic & Biopharma News

Baby teeth link autism and heavy metals, NIH study suggests
Scientists used lasers to map the growth rings in baby teeth generated during different developmental periods.
National Institutes of Health, 2017-06-01 18:30:00

Evzio price hikes boosted Kaléo's rebate bill but it hasn't paid up, PBM lawsuit claims
Kaléo Pharma's price hikes on the lifesaving overdose med Evzio haven’t only angered lawmakers. A leading pharmacy benefit manager, Express Scripts, is going after the tiny drugmaker for unpaid rebates triggered by the exponential price increases.
Fierce Pharma, 2017-06-01 17:56:01

TMS therapy offers hope for senior adults with depression
Late-life depression (LLD) is a frequent complication of the aging process, occurring in up to 5% of senior adults and in a higher proportion of subjects with coexistent medical illnesses.
News Medical Life Sciences, 2017-06-01 17:39:15

Insilico Medicine launches personalized drug discovery platform to develop new treatments for ALS
Today, Insilico Medicine, Inc., a company applying the latest advances in deep learning to biomarker development, drug discovery and aging research, launched ALS.AI, a personalized drug discovery and biomarker development platform utilizing the latest advances in deep learning.
News Medical Life Sciences, 2017-06-01 16:33:25

Differences in uptake of toxins, nutritional elements during late pregnancy and early life linked to ASD risk
Using evidence found in baby teeth, researchers from The Senator Frank R. Lautenberg Environmental Health Sciences Laboratory and The Seaver Autism Center for Research and Treatment at Mount Sinai found that differences in the uptake of multiple toxic and essential elements over the second and third trimesters and early postnatal periods are associated with the risk of developing autism spectrum disorders (ASD), according to a study published June 1 in the journal Nature Communications.
News Medical Life Sciences, 2017-06-01 16:15:28

NIH researchers find potential genetic cause of Cushing syndrome
Finding may lead to therapies that prevent pituitary tumor recurrence.
National Institutes of Health, 2017-06-01 16:15:00

Intensity’s Treatment Candidate Administered to First Solid Tumor Patient in Phase 1/2 Trial

Immuno-Oncology News, 2017-06-01 15:57:45

Tesaro and its new med Zejula are on the block, but bidders aren't rushing in: WSJ
Ahead of the year’s biggest cancer-data download, closely watched maker of oncology drugs Tesaro has put itself up for sale, the WSJ reports. Thanks to its blockbuster-to-be PARP inhibitor Zejula, Tesaro could sell for $9 billion-plus—if it does at all, that is.
Fierce Pharma, 2017-06-01 15:04:45

Scientists identify new gene that prompts muscle stem cells to fuse together
A detour on the road to regenerative medicine for people with muscular disorders is figuring out how to coax muscle stem cells to fuse together and form functioning skeletal muscle tissues.
News Medical Life Sciences, 2017-06-01 15:03:00