Genomic & Biopharma News

Researchers discover specific cellular pathway involved in lung tissue regeneration
Researchers at Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania have identified a cellular pathway that can be targeted with a naturally occurring drug to stimulate lung tissue regeneration, which is necessary for recovery from multiple lung injuries.
News Medical Life Sciences, 2020-09-28 23:52:17

Resveratrol and pterostilbene inhibit SARS-CoV-2 infection in vitro
A team of scientists at the University of Groningen, in the Netherlands, demonstrates that a natural plant product, resveratrol, and its structural analog, pterostilbene, have long-lasting antiviral effects against severe acute respiratory coronavirus 2 (SARS-CoV-2) infection. The study is currently available on the bioRxiv preprint server.
News Medical Life Sciences, 2020-09-28 23:50:39

Science academies present joint statement on health, sustainability, and digitization
In the run-up to the summit of the G20 countries in November 2020 to be held in Riyadh (Saudi Arabia), the science academies of these countries have presented their joint statement "Foresight: Science for Navigating Critical Transitions".
News Medical Life Sciences, 2020-09-28 23:47:02

ORB Employees Participate in 2019 Martin Luther King Day Event
ORB employees get a rare break from the lab on January 21, 2019. A group of Ocean Ridge Biosciences employees stepped out of the lab on a beautiful South Florida winter day to take part in an event honoring Martin Luther King. We got our hands dirty planting some flowers and shrubs at a local park in Deerfield Beach.
ORB Company News, 2019-01-22 23:24:59

Genetic testing is cost-effective, beneficial for newly diagnosed patients with metastatic GIST
Because gastrointestinal stromal tumors (GIST) are sensitive to the targeted small molecule therapy imatinib, oncologists tend to treat all patients with metastatic GIST with this drug. However, because this rare type of cancer is caused by different genetic mutations, imatinib does not help all patients equally.
News Medical Life Sciences, 2020-09-28 23:41:33

Harnessing the microbiome potential
Spring is underway in parts of the US, and while Florida by no means undergoes the dramatic reappearance of foliage or colorful clumps of daffodils and azaleas, the southern part of the sunshine state experiences its share of spring renewals.  For instance, recently a brood of Muscovy duck (Cairina moschata) hatchlings appeared near Ocean Ridge Biosciences' laboratory.
ORB Company Blog, 2017-03-31 21:41:45

Brain wiring genes may be linked to a significant portion of cerebral palsy cases
In an article published in Nature Genetics, researchers confirm that about 14% of all cases of cerebral palsy, a disabling brain disorder for which there are no cures, may be linked to a patient's genes and suggest that many of those genes control how brain circuits become wired during early development.
News Medical Life Sciences, 2020-09-28 23:36:23

FDA releases final guidance to improve patient communication about risks of breast implants
Today, the U.S. Food and Drug Administration issued the final guidance, "Breast Implants - Certain Labeling Recommendations to Improve Patient Communication," as part of the agency's effort to help improve the information available to patients and health care professionals about the risks of breast implants.
News Medical Life Sciences, 2020-09-28 23:30:33

Life-threatening COVID-19 associated with specific genetic variants
Results of a genome-wide association study on 2,244 critically-ill patients due to coronavirus disease (COVID-19) from 208 intensive care units across the United Kingdom revealed significant host-specific genetic determinants that can predispose people to the severe form of the disease. The report is currently available on the medRxiv preprint server.
News Medical Life Sciences, 2020-09-28 23:27:21

Blocking nuclear pore complex formation can help selectively kill cancer cells
Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that blocking the construction of nuclear pores complexes--large channels that control the flow of materials in and out of the cell nucleus--shrank aggressive tumors in mice while leaving healthy cells unharmed.
News Medical Life Sciences, 2020-09-28 23:20:58

Epigenetic changes in the brain drive late-onset Alzheimer's disease
New findings suggest that late-onset Alzheimer's Disease is driven by epigenetic changes -- how and when certain genes are turned on and off -- in the brain. Results were published today in Nature Genetics.
News Medical Life Sciences, 2020-09-28 23:15:08