Harnessing the microbiome potential


Spring is underway in parts of the US, and while Florida by no means undergoes the dramatic reappearance of foliage or colorful clumps of daffodils and azaleas, the southern part of the sunshine state experiences its share of spring renewals.
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Submitted by sheenak on Fri Mar 31, 2017 5:05 PM


ORB relocates to Deerfield Beach and celebrates grand opening of new facility with local researchers

After 8 years of operation in Palm Beach Gardens, Ocean Ridge Biosciences (ORB) has recently relocated to a 5,394 sq. ft. facility in Deerfield Beach, Florida.

The new facility provides several improvements which will enable ORB to provide improved and expanded services to academic and corporate clients. These include:

  • Large 475 sq. ft. negatively pressurized DNA testing lab
  • Six-foot Class II type B1 biological safety cabinet
  • Server/ freezer room cooled with a dedicated 5-ton AC unit
  • Ample laboratory bench space for 12-15 scientists
  • Pre-amp / sample preparation lab that is well isolated from the DNA testing lab
  • Conference room equipped with video conferencing capabilities
  • Total of 30 tons of AC cooling to maintain temperature and humidity in narrow tolerances
  • Entire lab facility backed up by three 16 kVA Uninterruptible Power Supplies
  • A 22 kW generator for backing up servers, freezers, and key AC units

In celebration of this step forward, ORB hosted a grand opening event on November 18th, 2016 with a ribbon cutting ceremony officiated by Vice Mayor of Deerfield Beach, Richard Rosenzweig and Larry DeVille, Executive Director of the Deerfield Beach Chamber of Commerce. In addition to members of the Deerfield Beach Chamber of Commerce and Greater Fort Lauderdale Alliance, over 80 local academia researchers, life science and business professionals attended the event.

Academic researchers, professors, and students from Palm Beach, Broward, and Miami-Dade counties joined the festivities. Those in attendance represented Florida Atlantic University, Palm Beach State College, Florida Scripps Research Institute, Palm Beach Atlantic University, Nova Southeastern University, Barry University, St. Thomas University, Florida International University, and the University of Miami.

Deerfield Beach biotechnology companies, such as Cell Science Systems, DNA International Labs, and Spector Scientific Lab warmly welcomed ORB to the area. Researchers and executives from additional neighboring life science companies such as Immunosite Technologies, Health Chem Diagnostics, Ovation Dx, CBS Labs, ECI Pharmaceuticals, Goodwin Biotechnology, and OPKO Health were present at the event and participated in laboratory tours and mini-lectures.

ORB staff members, Dr. David Willoughby and Sheena Knight, provided lectures on genomic technologies and biomarker discovery, respectively. Also, guest speaker Dr. Nira Savaraj, an oncologist at the Miami Veterans Administration Medical Center, spoke directly from her clinical experience about the importance of testing biomarkers with liquid biopsies with cancer patients to efficiently and accurately diagnosis patients and determine the best treatment course on a case-by-case basis.

In support of academic research as well as pharmaceutical and drug discovery companies’ investigations, ORB’s services packages are structured to include the identification and development biomarkers from a variety of biofluid samples, including whole blood, serum, plasma, salvia, and cerebrospinal fluid samples. Routinely ORB partners with investigators who seek to understand the efficacy of a treatment, unintended effects produced by therapeutics, or the impact of a drug on specific patient populations. Currently ORB is collaborating with researchers at the University of Miami on development of prognostic biomarkers relevant to immunotherapy for lung cancer and the identification of non-responders to PD-1 therapies in non-small lung cell cancer trials.

ORB greatly values the tremendous support from local academic researchers and biotech companies to honor the company’s move to an expanded and upgraded facility as well as the Deerfield Beach Chamber of Commerce’s enthusiastic welcome into this growing and vibrant community. ORB is excited to be in a ripe position to carve out a deeper niche in the biomarker discovery space with laser-focus on exosomes, circulating tumor cells, and circulating tumor nucleic acids during 2017.


Submitted by oceanrid on Mon Nov 21, 2016 2:02 PM


Circulating tumor DNA evaluated as an alternative to tissue NGS for non-small cell lung cancer


Tissue biopsies, which are currently the gold standard molecular diagnostic technique for oncologists, are not only painful to cancer patients, but expose an already immune-comprised population to increased rates of nosocomial infections.
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Submitted by sheenak on Fri Oct 21, 2016 1:01 PM


FierceBiotech's 2016 Fierce 15


It's that time of year again when new school routines are established, deciduous trees begin their showy transformation, and FierceBiotech releases its annual list of 15 innovative companies who are primed to make a big splash in the biopharma industry.
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Submitted by sheenak on Fri Sep 23, 2016 1:01 PM


Happy Birthday Charles


February 12th, 1809, Shrewsbury, England (UK).
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Submitted by AnnaLauraM on Fri Feb 12, 2016 2:02 PM


Palm Beach State Students tour Ocean Ridge Biosciences (2014-12-08)


On Monday November 25th, 2014 Ocean Ridge Biosciences (ORB) hosted a tour of the lab facility for Palm Beach State Biotechnology students.
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Submitted by sheenak on Mon Dec 8, 2014 1:01 PM


Characterization of small non-coding RNAs in human seminal exosomes. (2014-06-30)


Exosomes, extracellular microvesicles of 30-200 nanometers in diameter, have been detected in a wide variety of biological fluids including serum, saliva, urine and lymph.
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Submitted by davidw on Mon Jun 30, 2014 1:01 PM