Genomic & Biopharma News

Circulating tumor DNA evaluated as an alternative to tissue NGS for non-small cell lung cancer
Tissue biopsies, which are currently the gold standard molecular diagnostic technique for oncologists, are not only painful to cancer patients, but expose an already immune-comprised population to increased rates of nosocomial infections. Furthermore, it is not uncommon for the typical clinical pathology workflow to yield samples which are not suitable for routine analysis strategies, e.g.
ORB Company Blog, 2016-10-21 17:26:00

Neurocrine goes high—$60K-plus high—with price for new movement drug Ingrezza
Neurocrine goes high—$60K-plus high—with price for new movement drug Ingrezza chelfand Wed, 04/26/2017 - 08:54
Fierce Pharma, 2017-04-26 12:54:49

Artificial womb could improve survival among premature babies
Researchers have designed a womb-like device that could allow premature babies to develop their lungs and organs in the critical few weeks that remain before they face the outside world.
News Medical Life Sciences, 2017-04-26 12:21:43

Removal of Batch Effects from Single-cell RNA-Seq
Sources of variability in experimentally derived data include measurement error in addition to the physical phenomena of interest. This measurement error is a combination of systematic components, originating from the measuring instrument, and random measurement errors. Novel biological technologies, such as single-cell RNA-seq, are plagued with systematic errors that may severely affect statistical analysis if ...
Transcriptome Research & Industry News, 2017-04-26 12:15:58

Novartis, Pfizer and Amgen top pharma's lobby spending in eventful Q1
Novartis, Pfizer and Amgen top pharma's lobby spending in eventful Q1 esagonowsky Wed, 04/26/2017 - 07:58
Fierce Pharma, 2017-04-26 11:58:02

FDA warns 14 companies for illegal promotion and selling of cancer cure products
The U.S. Food and Drug Administration has issued warning letters today to 14 companies based out of U.S., who are selling more than 65 products illegally making false claims to prevent, diagnose, treat, or cure cancer.
News Medical Life Sciences, 2017-04-26 11:29:22

A double-filtration microfluidic device for isolation and detection of extracellular vesicles
Extracellular vesicles (EVs), including exosomes and microvesicles, are present in a variety of bodily fluids, and the concentration of these sub-cellular vesicles and their associated biomarkers (proteins, nucleic acids, and lipids) can be used to aid clinical diagnosis. Although ultracentrifugation is commonly used for isolation of EVs, it is highly time-consuming, labor-intensive and instrument-dependent for ...
Exosome RNA Research & Industry News, 2017-04-26 11:21:11

Exposure to variable temperatures may have positive effect on health
Exposure to environments outside a comfortable temperature could help tackle major metabolic diseases, such as diabetes and obesity, and should be reflected in modern building practices, finds a study published today.
News Medical Life Sciences, 2017-04-26 11:18:06

A robust and cost-effective approach to sequence and analyze complete genomes of small RNA viruses
Next-generation sequencing (NGS) allows ultra-deep sequencing of nucleic acids. The use of sequence-independent amplification of viral nucleic acids without utilization of target-specific primers provides advantages over traditional sequencing methods and allows detection of unsuspected variants and co-infecting agents. However, NGS is not widely used for small RNA viruses because of incorrectly perceived cost estimates and ...
Transcriptome Research & Industry News, 2017-04-26 11:07:37

FierceBiotech's 2016 Fierce 15
It's that time of year again when new school routines are established, deciduous trees begin their showy transformation, and FierceBiotech releases its annual list of 15 innovative companies who are primed to make a big splash in the biopharma industry.
ORB Company Blog, 2016-09-23 17:22:41

Study provides new insights on molecular mechanisms that impair muscle stem cells during aging
Researchers at Sanford Burnham Prebys Medical Discovery Institute have identified a previously unrecognized step in stem cell-mediated muscle regeneration.
News Medical Life Sciences, 2017-04-26 11:05:20